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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Fast Track, 2002
    Parkinson's and the Regulation of Neuronal Survival

    Parkinson's disease (PD) is an important neurological disorder that afflicts over one million North Americans and is characterized by gait difficulty, rigidity, and tremor. Although Symptoms & Side...

  • Fast Track, 2002
    Prospective study of nonsteroidal antiinflammatory drugs and risk of PD

    Although the exact cause of Parkinson's disease is unknown, the results of animal experiments and postmortem studies among individuals with Parkinson's disease suggest that inflammation may contribute...

  • Fast Track, 2002
    Levodopa-induced dyskinesias result from dysregulation of intraneuronal trafficking of dopamine receptors

    Involuntary movements, or dyskinesias, represent a debilitating complication of levodopa therapy for Parkinson's disease experienced by the vast majority of the patients. We hypothesize that...

  • Fast Track, 2002
    Alterations of the distribution and of the subunit composition of the N-methyl-D-aspartate receptors in the basal ganglia of the parkinsonian rat

    The loss of the dopamine-containing neurons of the substantia nigra, the major hallmark of Parkinson's disease, leads to many 'knock-on' effects in the brain, which include both structural and...

  • Fast Track, 2002
    Identification of Novel Dopamine Signaling Components Using C. Elegans Genetic Analysis

    Neurons communicate with one another in the brain using the neurotransmitter dopamine and this communication is critical for normal brain function. In Parkinson's patients the neurons that make...

  • Fast Track, 2002
    Comparitive gene expression analysis of the brain in Parkinson's Disease and in familial encephalopathy with neuroserpin inclusion bodies (FENIB): implications for pathogenesis

    Parkinson's disease (PD) is a common neurological disorder that affects the control of movement and frequently cognition. Examination of postmortem brain tissue from subjects with Parkinson's disease...

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