The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Improved Biomarkers and Clinical Outcome Measures, 2019GBA Sequencing and Detection of Mutations, Deletions, Insertions and Recombinations with the GBA Pseudo Gene
Study Rationale:
Mutations in the GBA gene are the most common genetic cause of Parkinson’s disease. This gene has a nearby pseudogene, which is a genetic material that is very similar to the original... -
Alpha-synculein Biology and Therapies, 2019Chaperones of Alpha-synuclein for Membrane Fusion Involved in Synaptic Transmission
Study Rationale:
Abnormal accumulation of the protein alpha-synuclein is a pathological hallmark of Parkinson’s disease (PD). We and others have evidence that aggregated alpha-synuclein could harm... -
Alpha-Synuclein Biology and Therapies, 2019Alpha-synuclein-Binding Proteins on the Cell Surface as Novel Therapeutic Targets
Study Rationale:
Alpha-synuclein is a sticky protein that clumps in the brains of people with Parkinson's disease (PD). Recent research suggests that clumps of alpha-synuclein spreads in the brain... -
Research Grant, 2019New Activators of Parkin
Study Rationale:
Parkin is a protein made by all cells in the body, including brain cells. It plays an important role in the protection of neurons through a process known as quality control. Changes... -
Research Grant, 2019Imaging Techniques to Evaluate LRRK2 Activity in Idiopathic Parkinson's Disease
Study Rationale:
Inherited mutations in the LRRK2 gene are a common cause of Parkinson's disease that presents with clinical symptoms and brain changes similar to idiopathic (cause unknown) Parkinson... -
Research Grant, 2019Computer Simulation of LRRK2 and GBA Interactions to Identify Therapeutic Targets for Parkinson's Disease
Promising Outcomes of Original Grant:
Our original project aimed to create a computer simulation of biological pathways involved in Parkinson's disease and how genetic mutations in LRRK2 can change...
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Our funding programs support basic, translational and clinical research from academia and industry.