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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2010
    Biofeedback-based Motor Learning to Ameliorate Freezing of Gait

    Objective/Rationale:  
    Our objective is to demonstrate that an intervention program based on motor learning principles can be applied to train subjects with Parkinson's disease (PD) who suffer from...

  • Biomarkers, 2010
    Prospective Validation of Risk Markers for the Development of Parkinson’s Disease

    Promising Outcomes of Original Grant:
    As Parkinson’s disease is diagnosed when already a number of neurons have degenerated the PRIPS cohort consisting of 1847 healthy subjects older than 50 years was...

  • Therapeutics Development Initiative, 2009
    Potential Efficacy of a Novel HDAC Inhibitor in Pre-clinical Models of Parkinson's Disease

    Objective/Rationale:
    Histone deacetylases (HDACs) are a family of enzymes that reduce gene expression and can regulate protein clearance. Inhibitors of HDACs have been reported to be efficacious in...

  • Biomarkers, 2007
    Prospective Validation of Risk Markers for the Development of Parkinson’s Disease

    Objective/Rationale:
    The development of disease-course modifying or neuroprotective treatments is still an unmet therapeutical need in Parkinson’s disease. Treatment will likely work best if initiated...

  • Research Grant, 2017
    Validation of the Clinical Dementia Rating Scale Sum of Boxes (CDR-SOB) for Parkinson's Disease

    Study Rationale:
    The US Food and Drug (FDA) requires acceptable outcome measures to approve a cognitive-enhancing medication for the treatment of mild cognitive impairment (MCI) in Parkinson's disease...

  • Research Grant, 2021
    Comparing the Effectiveness of Two Imaging Methods for Monitoring the Progression of Parkinson’s Disease

    Study Rationale:
    Parkinson’s disease robs the brain of dopamine, a neurochemical needed for normal movement and cognition. A variety of imaging methods can be used to monitor the brain’s dopamine...

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