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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2007
    Virtual Reality to Reduce Fall Risk in Patients with Parkinson’s Disease

    Objective/Rationale:
    Virtual Reality (VR) allows for training in complex environments, while motivating subjects to perform numerous repetitions of the training tasks under well-controlled conditions...

  • Fall 2021 RFP: Outcome Measures, 2022
    Development of Standardized Measurements for Monitoring the Progression of Parkinson’s Disease via MRI

    Study Rationale: One of the difficulties in research towards new treatments in Parkinson’s disease (PD) is the diversity of disease presentations and the lack of tools to measure the effect of a...

  • Therapeutics Development Initiative, 2008
    Development of ERb agonists for the treatment of Parkinson's Disease

    Objective/Rationale:
    Estrogens modulate many cerebral functions such as mental state, mood, cognition and locomotion. Data indicate that estrogens may slow down the development and progression of PD...

  • Rapid Response Innovation Awards, 2014
    Effect of Dietary Ketosis On Alpha-Synuclein Accumulation

    Study Rationale:
    A key feature of Parkinson’s disease is abnormal accumulation of the protein alpha-synuclein. Production of organic compounds called ketones is a normal metabolic process that occurs...

  • MJFF Research Grant, 2011
    fMRI of First Degree Relatives of LRRK2 Positive PD Patients

    Objective/Rationale:

    First, to study the effect of the presence of the LRRK2 G2019S mutation on brain activation patterns in Parkinson’s disease (PD) patients who recently converted into a diseased...

  • Biomarkers to Support Therapeutic Trials Program, 2023
    Using Neurophysiology as a Stratification Tool for Synucleinopathy

    Study Rationale: Although numerous disease-modifying drugs are being developed for Parkinson’s disease (PD), the current methods used to identify people suitable for clinical trials are costly...

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