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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Biomarkers to Support Therapeutic Trials Program, 2023
    Using Neurophysiology as a Stratification Tool for Synucleinopathy

    Study Rationale: Although numerous disease-modifying drugs are being developed for Parkinson’s disease (PD), the current methods used to identify people suitable for clinical trials are costly...

  • Rapid Response Innovation Awards, 2014
    Neuroimaging Carriers of the Alpha-synuclein E46K Mutation as a Model of Idiopathic Lewy Body Disease

    Study Rationale:
    In 2004 our group described, for the first time in literature, the E46K mutation of the alpha-synuclein gene in a family from the Basque region of Spain. The rare E46K mutation is...

  • Therapeutic Pipeline Program, 2015
    Effects of Transcranial Stimulation on Freezing of Gait in Parkinson's Disease

    Study Rationale:
    Many people with Parkinson's disease experience freezing of gait, when the person is unable to move forward, despite his or her best efforts. Although it is not exactly clear why or...

  • Access to Data and Biospecimens, 2015
    BioFIND: Analysis of A-beta, Tau and P-tau in CSF Samples

    Study Rationale: Mixed pathology is common in all neurodegenerative diseases including Parkinson’s disease (PD).  Three cerebrospinal fluid (CSF) biomarkers, Ab1-42, t-tau and p-tau181, provide an...

  • Biosample and Tissue Resource, 2013
    Relationship of Vitamin B12 Status and Parkinson's Disease

    Objective/Rationale:             
    Vitamin B12 deficiency can cause a number of neurological symptoms, including instability, neuropathy (which may cause numbness and tingling) and cognitive defects...

  • PD Subtypes, 2007
    Defining PD Subtypes Based on Patterns of Long-term Outcome

    The purpose of our study is to identify Parkinson’s disease subtypes based on how individuals are doing approximately seven to eight years after diagnosis. Some patients have few symptoms at this time...

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