The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2011Alpha-synuclein and Tau Mislocalization to Dendritic Spines
Objective/Rationale:
In addition to motor disorders, Parkinson disease (PD) patients also suffer from cognitive deficits, which are believed to result from abnormal accumulation of alpha-synuclein, a... -
Therapeutic Pipeline Program, 2015Improving Access to Depression Care in Parkinson’s Disease: A Telehealth Approach
Study Rationale:
There is a critical need for treatments that address depression and barriers to care among the approximately 5 million people living with Parkinson’s disease (PD)... -
Repositioning Drugs for PD, 2011Evaluation of a Specific DAT Inhibitor in Pre-clinical Models of Parkinson's Disease
Objective/Rationale:
MLR-1017 is a psychostimulant drug used clinically for a variety of neuropsychiatric and other applications, but has never been tested in Parkinson’s disease (PD). Levodopa is a... -
Research Grant, 2018Charting a Path to Success for Clinical Trials in Patients with Inherited, GBA-linked Parkinson's Disease: PPMI Supplement
Promising Outcomes of Original Grant:
The original study is ongoing.Objectives for Supplemental Investigation:
We aim to determine whether fatty molecules called sphingolipids can serve as biomarkers --... -
Rapid Response Innovation Awards, 2014Optogenetics-based, Photo-switchable Model of Parkinson’s Disease for Drug Screening
Objective/Rationale:
Neurodegeneration has proven notoriously difficult to study. The main barrier to progress has been the challenging, heterogeneous nature of brain tissue. Optogenetics is a... -
Community Fast Track, 2003Regulation of Dopaminergic Pathways by Eph Family Receptors
Replacing dopaminergic neurons is an attractive alternative in the treatment of Parkinson's disease (PD). However, a successful treatment relies not only on the introduction of new neurons, but also...
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Our funding programs support basic, translational and clinical research from academia and industry.