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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2018
    Searching Brain Scan Data for Patterns of Activity Associated with Parkinson's Disease

    Study Rationale:
    There is a pressing need for Parkinson's disease (PD) biomarkers -- objective measures of disease -- that will enable early and accurate diagnosis and allow to track disease...

  • Rapid Response Innovation Awards, 2011
    Alpha-synuclein and Tau Mislocalization to Dendritic Spines

    Objective/Rationale:
    In addition to motor disorders, Parkinson disease (PD) patients also suffer from cognitive deficits, which are believed to result from abnormal accumulation of alpha-synuclein, a...

  • Therapeutic Pipeline Program, 2015
    Improving Access to Depression Care in Parkinson’s Disease: A Telehealth Approach

    Study Rationale:                   
    There is a critical need for treatments that address depression and barriers to care among the approximately 5 million people living with Parkinson’s disease (PD)...

  • Repositioning Drugs for PD, 2011
    Evaluation of a Specific DAT Inhibitor in Pre-clinical Models of Parkinson's Disease

    Objective/Rationale: 
    MLR-1017 is a psychostimulant drug used clinically for a variety of neuropsychiatric and other applications, but has never been tested in Parkinson’s disease (PD). Levodopa is a...

  • Research Grant, 2018
    Charting a Path to Success for Clinical Trials in Patients with Inherited, GBA-linked Parkinson's Disease: PPMI Supplement

    Promising Outcomes of Original Grant:
    The original study is ongoing.

    Objectives for Supplemental Investigation:
    We aim to determine whether fatty molecules called sphingolipids can serve as biomarkers --...

  • Rapid Response Innovation Awards, 2014
    Optogenetics-based, Photo-switchable Model of Parkinson’s Disease for Drug Screening

    Objective/Rationale:
    Neurodegeneration has proven notoriously difficult to study. The main barrier to progress has been the challenging, heterogeneous nature of brain tissue. Optogenetics is a...

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Our funding programs support basic, translational and clinical research from academia and industry.

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