The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2012Pre-clinical Safety Study of LRRK2 Inhibitors
Objective/Rationale:
LRRK2 is well recognized as a potential central nervous system target for the treatment of Parkinson’s disease (PD). For development as possible therapeutic drugs...
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Resource: Utilizing DATATOP Biospecimens, 2012Small-molecule PD Biomarkers: a Metabolomic Analysis
Objective/Rationale:
Based on our earlier findings that yielded several promising biomarkers, this metabolomic study of small-molecule biochemicals will investigate specimens from... -
Dyskinesia LEAPS, 2012Xenon Inhalation to Reduce L-DOPA-Induced Dyskinesia
Levodopa is the most effective drug to treat symptoms of Parkinson’s disease, however long-term use leads to disabling L-DOPA-induced dyskinesia (LID) in the vast majority of patients. NMDA receptor...
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MJFF Research Grant, 2012Intrinsic Remodeling of the Fovea in Parkinson’s Disease
Promising Outcomes of Original Grant:
In the past we determined the part of the retina (the back of the eye) which needs to be measured for PD induced changes. We developed an equation which permits... -
MJFF Research Grant, 2012Bay Area Solvent Study - Symptoms (BASS-S)
Objective/Rationale:
Chlorinated solvents are commonly used in a variety of occupations. The solvents trichloroethylene (TCE) and perchloroethylene (PERC) have been associated with an... -
Improving Levodopa Delivery, 2012Enhanced Dopamine Availability, Prolonged Activity and Improved Dyskinesia Profile After Administration of Selectively Deuterated Levodopa
Objective/Rationale:
To confirm the found beneficial effects of DP-102 (reduced dyskinetic effects at motoric equieffective doses in comparison to regular levodopa) in a pre-clinical model of Parkinson...
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Our funding programs support basic, translational and clinical research from academia and industry.