The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2020Alpha-synuclein Toxicity in LRRK2 Knock-in Models and Rescue by LRRK2 Silencing
Study Rationale:
Gene mutations that alter the function of the LRRK2 protein are known to increase the risk of developing Parkinson’s disease (PD). One of the pathological hallmarks of PD is the... -
Non-pharmacological Interventions for Gait and Balance, 2019Protective Step Training in People with Parkinson's Disease and Postural Disturbances
Study Rationale:
Falls are a common and challenging symptom of Parkinson's disease. The ability to execute a quick and effective movement after a loss of balance (e.g., a "protective step") may reduce... -
Research Grant, 2016Planning Phase for a Phase IIa Study of Nilotinib in People with Parkinson's Disease
Study Rationale:
Nilotinib, a drug approved for chronic myelogenous leukemia, inhibits the protein c-Abl. Higher brain levels of c-Abl are associated with Parkinson's disease (PD), and laboratory...
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Biosample and Tissue Resource, 2013From Genetic Risk Toward Genetic Prognosis
Objective/Rationale:
The progression and prognosis of Parkinson’s disease (PD) varies considerably between individual patients — ranging from a manageable, functional decline to an aggressive course... -
LRRK2 Cohort Consortium, 2012Parkinson’s Institute LRRK2 Cohort: Clinical Phenotype, Pre/Non-Motor and Environmental Risk Assessment
Objective/Rationale:
The objective of this award is to better understand the clinical symptoms of patients that carry the most common genetic risk factor for PD the LRRK2 G2019S variant and what role... -
MJFF Research Grant, 2009The Validation of Anxiety Scales in Parkinson's Disease
Objective/Rationale:
This study has two objectives:
1. To assess the occurrence and symptoms of anxiety disorders in Parkinson's disease, including atypical anxiety syndromes, and anxiety states...
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Our funding programs support basic, translational and clinical research from academia and industry.