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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Parkinson’s Pathway Molecular Data Analysis Program, 2022
    Interaction of Mitochondrial Genes and Lifestyle Factors on Age at Onset in Parkinson’s Disease

    Study Rationale: Cellular structures called mitochondria are functionally impaired in Parkinson’s disease (PD). How environmental toxins or lifestyle factors influence mitochondrial function and...

  • Research Grant, 2022
    Registry for the Advancement of DBS in Parkinson’s Disease (RAD-PD)

    Study Rationale: RAD-PD is a quality improvement patient registry project that will address clinical questions about deep brain stimulation (DBS) therapy that cannot be practically answered via the...

  • Summer 2022 RFP: Accelerating the Translation of Parkinson's Disease Therapies, 2022
    Developing an Inhibitor of Transglutaminase 2 as a Disease-modifying Treatment for Parkinson’s Disease

    Study Rationale: Clumping of alpha-synuclein in the brain is a key pathological feature of Parkinson’s disease (PD) and is believed to lead to brain cell degeneration. Identifying factors that...

  • Research Grant, 2022
    Development of a Radiolabeled Tracer for Detecting Insoluble Protein Aggregates in Parkinson’s Disease

    Study Rationale: Many neurodegenerative disorders are caused by a toxic buildup of insoluble protein aggregates.  In Parkinson’s disease (PD), accumulation of alpha-synuclein contributes to the death...

  • Research Grant, 2022
    Monitoring Prodromal and De Novo Parkinson’s Disease (PRONOVO) Using Multi-modal Imaging

    Study Rationale: Individuals with Parkinson’s disease (PD) display variable impairment of the brain and peripheral nervous system, suggesting that PD includes a range of subtypes. Yet the underlying...

  • Research Grant, 2022
    Development of PET Tracer for Imaging SV2C in Parkinson's Disease

    Study Rationale: Cells in the brain uses molecules such as dopamine, the neurotransmitter that is depleted in people with Parkinson’s disease (PD), to transmit signals from one to another. The...

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