The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Resource: Utilizing DATATOP Biospecimens, 2011Using Human Cerebrospinal Fluid Samples Collected in DATATOP Study for Biomarker Validation in Patients with Parkinson disease
Objective/Rationale:
One of the major challenges in biomarker discovery/validation for Parkinson's disease (PD) is to define their utility in PD progression. This task is best tackled with the... -
Rapid Response Innovation Awards, 2011Unlimited Discovery of Non-Coding, Regulatory RNAs and Aberrant Splicing in Parkinson's
Objective/Rationale:
The recent discovery of a hidden universe of regulatory, non-coding transcripts and previously unknown variants of protein-coding transcripts is challenging conventional thinking... -
Biomarkers, 2011Development of an MRI-based Imaging Biomarker for the Detection of Alpha-Synuclein in Parkinson's disease
Objective/Rationale:
Parkinson’s disease is associated with accumulation of the protein α-synuclein in the brain, however, it is not currently possible to detect α-synuclein in the brain of Parkinson... -
Target Validation, 2011Preferential Targeting of Subpopulations of 5-HT1A Receptors
Objective/Rationale:
Although Parkinson's disease (PD) is primarily caused by dopamine dysfunction, function of serotonin (another neurotransmitter) is also affected. This suggests that serotonergic... -
Research Grant, 2011Targeting Glia in PD with Novel Anti-inflammatory Therapeutics
Objective/Rationale:
Loss of dopamine-producing neurons in Parkinson’s disease (PD) is accompanied by inflammation in surrounding support cells, called glial cells. This inflammatory state in glial... -
LRRK2 Target Engagement Ligand, 2011Development of LRRK2 Target Engagement Ligands
Objective/Rationale:
The overall objective of this project is to generate the data necessary to ultimately identify a small organic molecule capable of binding to a sub-domain of the LRRK2 protein...
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Our funding programs support basic, translational and clinical research from academia and industry.