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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Therapeutic Pipeline Program, 2013
    Exenatide as a Treatment for Patients with Parkinson’s Disease

    Objective/Rationale:             
    Laboratory data from several teams have indicated potential beneficial effects of the drug Exenatide on the survival of dopamine cells. In a small group of patients...

  • Dyskinesia Challenge, 2012
    The Effects of Memantine on Levodopa Induced Dyskinesias (LIDs) in MPTP-treated Pre-clinical Models

    Objective/Rationale:
    Levodopa is the mainstay of treatment for the motor symptoms of Parkinson’s disease.  Unfortunately one of the long term side effects of levodopa treatment is the development of...

  • MJFF Research Grant, 2011
    Ghrelin Concentrations in CSF and Corresponding Serum Samples in PD Patients and Controls

    Objective/Rationale:
    The aim of this study is to establish a valid method for measuring ghrelin concentrations in human cerebrospinal fluid samples. Ghrelin is an appetite-stimulating hormone with...

  • Clinical Intervention Awards, 2009
    MASTER PD: Magnetic Stimulation for the Treatment of Motor and Mood Symptoms of Parkinson's Disease: A Four-Center, Sham-Controlled, Parallel Group Study

    Objective/Rationale:
    To determine the efficacy and duration of benefit of noninvasive brain stimulation with repetitive transcranial magnetic stimulation (rTMS) to modulate brain activity in order to...

  • Edmond J. Safra Movement Disorders Research Career Development Award, 2024
    Towards a Better Understanding of Treatment-refractory Gait Issues in Parkinson’s Disease

    Study Rationale: Freezing of gait (FOG) is a sudden arrest of gait despite the intention to continue walking, often while a person is turning, walking in a confined space or is in a situation that...

  • Therapeutics Development Initiative, 2012
    Novel Fumarate Esters as Neuroprotective Agents in Parkinson’s Disease

    Objective/Rationale:
    Fumaric acid esters have shown immuno-modulatory and neuroprotective effects in cell-based systems,  pre-clinical models of disease and clinical trials in multiple sclerosis and...

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