The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2010Screen for Novel Glucocerebrosidase-Interacting Parkinson's Genes
Objective/Rationale:
Our goal is to discover new genes that lead to Parkinson’s disease. Most of the known causes of Parkinson’s disease are rare and account for a minority of patients. However, it... -
Rapid Response Innovation Awards, 2010Nasal PD Treatment-Proof-of-Concept
Objective/Rationale:
- In animal models of PD, brain injections of certain neurotrophic factors prevent degeneration of midbrain dopaminergic neurons.
- Clinical testing of brain injected gene vectors...
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Rapid Response Innovation Awards, 2010Functional Genomic Screening to Identify Novel Regulators of Parkin
Objective/Rationale:
In normal cells, Parkin protein senses damage of critical cellular organelles known as mitochondria and promotes recycling of their contents. Mitochondria are the energy... -
MJFF Research Grant, 2010Role of H1N1 Influenza Virus in the Etiology of Parkinson's Disease
Objective/Rationale:
Viruses (including influenza) have also been proposed to be an etiological agent for PD based on the appearance of otherwise non-explained clusters of parkinsonism. Recently... -
Rapid Response Innovation Awards, 2010Characterization of PARK16
Objective/Rationale:
Recently, a novel region of the genome containing genetic information predisposing to the development of Parkinson’s disease has been discovered through a collaborative study of... -
Rapid Response Innovation Awards, 2010Deciphering the Molecular Effects of Alpha-Synuclein in the Nucleus: DNA Binding and Transcriptional Dysregulation
Objective/Rationale:
A-synuclein, the main component of Lewy bodies, is thought to be present mostly on nerve terminals. Although the function of a-synuclein is unclear, its presence in the nucleus of...
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Our funding programs support basic, translational and clinical research from academia and industry.