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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2007
    Using Drosophila models of Parkinson’s disease to study the neuroprotective potential of tobacco and coffee

    Objective/Rationale:
    Tobacco and coffee users develop Parkinson’s disease at a significantly lower frequency than the general public. While there are several possible interpretations of these findings...

  • Rapid Response Innovation Awards, 2007
    Ghrelin Protects Nigral Dopamine Neurons

    Objective/Rationale:
    Our preliminary findings indicate that the gut hormone, ghrelin, has a major impact on the functionality and protection of nigrostriatal dopamine neurons. We, therefore, will test...

  • Rapid Response Innovation Awards, 2007
    Feasibility of Intranasal Delivery of GDNF for Parkinson's Disease

    Objective/Rationale:
    Glial cell line-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons. The therapeutic potential of GDNF for Parkinson...

  • Rapid Response Innovation Awards, 2007
    Virtual Reality to Reduce Fall Risk in Patients with Parkinson’s Disease

    Objective/Rationale:
    Virtual Reality (VR) allows for training in complex environments, while motivating subjects to perform numerous repetitions of the training tasks under well-controlled conditions...

  • LEAPS, 2007
    Discovery of mGluR4 Potentiators for Symptoms & Side Effects and Disease-Modifying Treatment of PD

    Objective/Rationale: 
    Surgical approaches to treatment of Parkinson’s disease using deep brain stimulation and corrective lesions provide valuable insights into novel approaches for treatment of this...

  • Biomarkers, 2007
    A Gene Expression Signature for the Early Detection of Parkinson Disease

    Objective/Rationale:
    The primary goal for the project is to develop a highly accurate and reproducible gene expression signature in blood to discriminate Parkinson disease both from other closely...

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