The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Community Fast Track, 2006The Role of Serotonin Neurons in the Induction of Dyskinesia in Grafted and L-DOPA-primed Animals
Levodopa, which is the most commonly used medication for patients with Parkinson's disease, is a beneficial therapy, but as the disease progresses it can be the cause of debilitating involuntary...
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MJFF Research Grant, 2006A Phase II Clinical Trial of Neurturin (NTN) Gene Therapy for PD
Objective/Rationale:
Neurotrophic factors including neurturin (NTN) have been shown to effectively augment the function and prevent the death of dopaminergic nigrostriatal neurons in animal models of... -
MJFF Research Grant, 2006The Unified Dyskinesia Rating Scale (UDysRS): Clinimetric Testing Program
In Parkinson’s disease, one of the most troubling clinical issues for prevention and management is drug-induced dyskinesia. Dyskinesias are abnormal and involuntary movements that relate in part to...
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MJFF Research Grant, 2006PDGene
Parkinson’s disease is a genetically complex and heterogeneous disorder. To date, mutations in five genes have been identified to cause early-onset parkinsonism, which typically follows Mendelian...
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MJFF Research Grant, 2006California Parkinson's Disease Registry Pilot Project
Much remains to be elucidated about causes of Parkinson’s disease, a progressive neurodegenerative condition that affects at least 1,000,000 people in the United States. For example, little detailed...
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Cell Line, 2006Improving the Long-term Survival & Functionality of the Transplanted Human Dopaminergic Neurons Through Space Creation Strategy
Dr. Xuejun Wen was awarded a one-year award in 2004 as part of the MJFF Cell Line II program. Dr. Wen proposed to test a novel biodegradable ‘spacer’ device to improve embryonic stem (ES) cell-derived...
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Our funding programs support basic, translational and clinical research from academia and industry.