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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Dopamine-Non-Responsive Symptoms of Parkinson's Disease, 2006
    The ReStore Study

    Apathy is a syndrome characterized by a primary lack of motivation and is manifested as a lack of effort and productivity, dependence on others for structuring daily activities, loss of interest in...

  • Dopamine-Non-Responsive Symptoms of Parkinson's Disease, 2006
    Development of a Model of Postural Disturbance by Lesioning Non-cholinergic Neurons

    Mounting evidence suggests that a small structure at the bottom of the brain called pedunculopontine nucleus is involved in the development of gait failure and postural instability in PD. We propose...

  • Dopamine-Non-Responsive Symptoms of Parkinson's Disease, 2006
    Evaluation of gastrointestinal motility in parkinsonian rodents

    Gastrointestinal (GI) symptoms, such as nausea, bloating, and constipation occur in nearly every patient afflicted with Parkinson's Disease (PD) at some point in their illness. These symptoms on their...

  • Dopamine-Non-Responsive Symptoms of Parkinson's Disease, 2006
    Non-dopaminergic imaging biomarkers as tools for early PD - testing the Braak Hypothesis

    Many recent studies have suggested that we need to expand research in Parkinson's disease to study symptoms other than the typical motor symptoms of tremor, slowness of movements, stiffness, and...

  • Dopamine-Non-Responsive Symptoms of Parkinson's Disease, 2006
    Freezing in Parkinson’s Disease: Clinical, Electrophysiological and Therapeutic Studies

    Gait disorders and Freezing of Gait (FOG) are among the very common, disabling and poorly understood symptoms of Parkinson's disease. FOG is a debilitating phenomenon in which the person is suddenly...

  • Dopamine-Non-Responsive Symptoms of Parkinson's Disease, 2006
    Treadmill Training and Gait-Related Disability in Parkinson’s Disease

    Gait impairment resulting in loss of mobility is a major cause of disability in Parkinson's disease, and current therapy including levodopa, surgery and rehabilitation are inadequate to preserve...

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