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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Fast Track, 2001
    Caffeine and the Risks of Disease Progression and Dyskinesias in PD

    A remarkable convergence of recent epidemiological and laboratory data has raised the possibility that dietary caffeine may reduce the risk of developing Parkinson's disease (PD). In our animal...

  • Fast Track, 2001
    Efficient Generation and Transplantation of Dopamine Neurons Derived from Cloned Pre-Clinical Model Embryonic Stem Cells

    In previous work, we have successfully generated functional dopamine neurons from both fetal CNS- and embryonic stem cells in animals. More recently (in collaboration with Rockefeller University) we...

  • Fast Track, 2001
    Multipotent Stem Cell Therapy for Parkinson's Disease

    We have identified stem cells in post-natal marrow of humans and animals that can be induced to differentiate at the clonal level to cells of mesodermal, neuroectodermal, and endodermal origin...

  • Fast Track, 2001
    Functional Consequences of Glutathione-Mixed Disulfide Formation in Brain Mitochondria

    Glutathione depletion and mitochondrial defects have been implicated in the etiology of Parkinson's disease (PD). Our previous work examined the cellular mechanisms underlying dopamine cell loss in...

  • Fast Track, 2001
    Synuclein, Parkinson's Disease and Strategies for Neuroprotection

    Parkinson's disease results from a loss of dopamine neurons in brain areas that control body movement. However, the cause of this loss is unknown and thus it has been difficult to develop rational...

  • Research Grant, 2000
    Targeting Serotonin Transporters for the Treatment of Levodopa-induced Dyskinesia Supplement

    Promising Outcomes of Original Grant:
    Initial studies of compounds acting on the serotonin transporter (SERT) for the treatment of levodopa-induced dyskinesia (LID) revealed, as hypothesized, that...

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