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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2014
    Inhibition of Striatal-Enriched Phosphatase (STEP) to Improve Parkinson-Related Cognitive Dysfunction

    Study Rationale:                   
    As the enzyme striatal-enriched phosphatase (STEP) may be abnormally elevated in aged parkinsonian pre-clinical models with cognitive deficits, the possibility...

  • Research Grant, 2020
    Parkinson’s Disease with Mild Cognitive Impairment Treated with a Nicotinic Agonist Drug

    Study Rationale:
    Parkinson’s disease with mild cognitive impairment (PD-MCI) is common, has important clinical consequences, and there is currently no treatment available. The underlying pathology of...

  • Repositioning Drugs for PD, 2011
    Droxidopa Treatment for Cognitive Impairment in Parkinson's Disease

    Objective/Rationale:
    Memory, concentration, and other cognitive operations are sometimes impaired in Parkinson's disease (PD), but available treatment options are very limited. This project will test...

  • Research Grant, 2018
    Safety and Tolerability of GRF6021 Infusions in People with Parkinson's Disease and Cognitive Impairment

    Study Rationale & Design:
    Components of blood have been found to improve health and enhance multiple biological functions, including brain function, in older animals. Blood plasma has been...

  • MJFF Research Grant, 2012
    The Role of Amyloid in the Progression of Cognitive Impairment in PD: A Prospective Cohort Study

    Objective/Rationale:             
    Dementia is a frequent and devastating non-motor complication of Parkinson's disease (PD). Although loss of dopamine producing brain cells play a role in cognitive...

  • Improved Biomarkers and Clinical Outcome Measures, 2019
    Correlating MRI, Pathology and Cognitive Assessments toward Biomarkers of Cognitive Decline

    Study Rationale:
    Parkinson’s studies are working to identify magnetic resonance imaging (MRI) biomarkers for early diagnosis, disease severity and progression. However, attempts to explore how brain...

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