The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Aligning Science Across Parkinson's, 2021Dual Role of Neural Activity in Parkinson’s Disease
Study Rationale:
Previous work has shown how the loss of dopamine neurons affects brain activity. In this program, we will determine how brain activity influences the neurodegeneration that causes... -
Aligning Science Across Parkinson's, 2021Role of Enteroendocrine Cells in the Origin of Parkinson's Pathology
Study Rationale:
Emerging evidence supports the concept that alpha-synuclein pathology, a hallmark of Parkinson’s disease (PD), might originate in the gastrointestinal tract and spread to the brain... -
Aligning Science Across Parkinson's, 2021Reconstituting the Lost Nigrostriatal Circuitry in Parkinson’s Disease
Study Rationale:
We recently discovered that it is possible to generate new neurons to rebuild the damage neural circuitries in a Parkinson’s disease model. This establishes a new foundation for... -
Aligning Science Across Parkinson's, 2021Gut-to-brain Circuit Contributions to Parkinson-like Phenotypes in Disease Models
Study Rationale:
Although clinicians have long reported that Parkinson’s disease (PD) does not affect the brain alone, the field has only recently started to investigate gut dysfunction in... -
Aligning Science Across Parkinson's, 2021Alpha-synuclein Effects on Gut-brain Circuits and Pre-motor Symptoms in Parkinson’s Disease
Study Rationale:
A hallmark of Parkinson’s disease (PD) is the development of abnormal deposits throughout the brain composed of the alpha-synuclein protein. This pathology can also be found in the... -
Aligning Science Across Parkinson's, 2021Olfactory Circuits: Alpha-Synuclein-Rich Neurons Respond to Environmental Triggers at the Origin of Parkinson’s Disease
Study Rationale:
To slow the progression of Parkinson's disease (PD), we need to know more about how it starts. It is well known now that many individuals with PD have had a significant reduction in...
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Our funding programs support basic, translational and clinical research from academia and industry.