The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2012The Role of Amyloid in the Progression of Cognitive Impairment in PD: A Prospective Cohort Study
Objective/Rationale:
Dementia is a frequent and devastating non-motor complication of Parkinson's disease (PD). Although loss of dopamine producing brain cells play a role in cognitive... -
Summer 2025 RFP: Accelerating Biological Understanding and Translational Approaches for PD Program - Biology, 2025Treatment of APOE4-associated Cognitive Decline in Parkinson’s Disease by an Adeno-associated Virus Coding for the Combined APOE2 and APOE-Christchurch Variants
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Summer 2025 RFA: Personalized Approaches for Understanding, Assessing and Improving Gait in Parkinson’s Disease Research Program, 2025Predicting Freezing of Gait in Parkinson’s Disease: An Objective Quantitative Exploration Combining Patient Perception with Multi-Dimensional Digital Gait Analysis & Multi-Domain Cognitive Testing
Study Rationale: Freezing of gait (FOG) is a debilitating – and not well understood - symptom impacting many patients with Parkinson’s disease (PwPD). FOG can occur during any stage of the disease but...
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Target Validation, 2010Treating Early Cognitive Impairments and Associated Movement Control Deficits by Stimulating alpha4beta2* nAChRs
Objective/Rationale:
Cholinergic systems decline early in PD and are hypothesized to contribute to cognitive impairments as well as to impairments in performing complex movements and postural... -
Critical Challenges in PD: Postural Instability and Gait Dis, 2012Targeted Cognitive Training Program for Freezing of Gait
Promising Outcomes of Original Grant:
In our original study we investigated the processes underlying the freezing phenomenon in PD. In this work we found symptoms of freezing of gait (FOG) could be... -
Cognitive Deficits and Mood Disorders in Parkinson's Disease, 2008Validation of the Dopamine-depleted CHT Hemizygous Pre-Clinical Model as an Animal Model of Parkinson's Disease with Dementia
Objective/Rationale:
Parkinson’s disease is traditionally thought of as a motor disorder. However, in addition to problems with movements, patients frequently develop cognitive problems leading to...
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Our funding programs support basic, translational and clinical research from academia and industry.