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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Target Advancement Program, 2021
    Targeting the Body’s Circadian Clock to Improve Sleep Quality in Parkinson’s Disease

    Study Rationale:
    Chronic sleep disruption is among the most frequently reported and disabling pathological features of Parkinson’s disease (PD). This loss of sleep quality is driven by dysregulation...

  • Target Advancement Program, 2021
    Sex-based Modulation of Neuromelanin-linked Parkinson’s Disease Pathology

    Study Rationale:
    Parkinson’s disease (PD) is more common in men than in women, and men with PD exhibit earlier onset, faster progression, more severe motor symptoms and more frequent cognitive decline...

  • Biomarkers, 2021
    Autoimmune Targeting of Mitochondria as a New Biomarker for Parkinson’s Disease

    Study Rationale:
    Parkinson’s disease (PD) is a complex, age-related disorder for which there are currently no biomarkers available to diagnose or predict the onset of disease. However, growing...

  • Research Grant Supplement, 2021
    The Role of LRRK2 in the Accumulation and Spread of Tau Protein

    Study Rationale:
    Although most cases of Parkinson’s disease (PD) have no known genetic cause, a subset is driven by mutations in a gene called LRRK2 (leucine-rich repeat kinase 2). Further, evidence...

  • Environmental Risk Factors, 2021
    Nationwide Geographic Cluster Analysis of Incident Parkinson’s Disease

    Study Rationale:
    The causes of Parkinson’s disease (PD) are mostly unknown, but non-genetic factors, such as environmental exposures during one’s lifetime, probably affect whether a person develops PD...

  • Environmental Risk Factors, 2021
    Exposure to Ambient Air Pollution and Risk of Parkinson’s Disease

    Study Rationale:
    Ambient (outdoor) air pollution can increase the risk of cardiovascular diseases and death. Some evidence links ambient air pollution to higher risk of Parkinson’s disease. But...

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