Funded Studies

Study Rationale:
Many people with Parkinson’s disease develop untreatable cognitive symptoms, including problems with attention, decision-making, and dementia at late stages of the disease, due to...

Study Rationale:
While neurodegeneration in Parkinson’s disease (PD) affects many cells, dopamine neurons are particularly vulnerable, and their loss drives many of the major motor difficulties in PD...

Study Rationale:
Nerve cells that produce the brain chemical dopamine die in people with Parkinson’s disease. These dopamine-producing nerve cells extend very long and thin fibers called axons that...

Study Rationale:
Previous work has shown how the loss of dopamine neurons affects brain activity. In this program, we will determine how brain activity influences the neurodegeneration that causes...

Study Rationale:
Emerging evidence supports the concept that alpha-synuclein pathology, a hallmark of Parkinson’s disease (PD), might originate in the gastrointestinal tract and spread to the brain...

Study Rationale:
We recently discovered that it is possible to generate new neurons to rebuild the damage neural circuitries in a Parkinson’s disease model. This establishes a new foundation for...