The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2020GBA Variations, Cholinergic Degeneration, and Cognitive Decline in Parkinson’s Disease
Study Rationale:
Mutations in the GBA gene are the most common genetic risk factors for Parkinson’s disease. People with GBA mutations (GBA-PD) may develop the disease at a younger age and may have... -
Research Grant, 2020Safety and Tolerability of NLX-112 in People with Parkinson’s
Study Rationale:
Motor symptoms of Parkinson’s disease are caused by a lack of brain neurons that carry a neurotransmitter called dopamine, and are commonly treated with levodopa. However, after... -
Research Grant, 2020Parkinson’s Disease Subtyping by Genetic and Intestinal Inflammation Biomarkers
Study Rationale:
Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. Currently, no drugs are available to treat or prevent the disease because the processes... -
Biosample Use Program, 2020Single-molecule Detection of Oligomeric Synuclein in Body Fluids
Study Rationale:
Clumps, or aggregates, of the protein alpha-synuclein have been detected in spinal fluid of people with Parkinson’s disease, where its concentration shows potential to be a biomarker... -
Research Grant, 2020RT-QuIC Assay for Alpha-synuclein in Incidental Lewy Body Disease
Study Rationale:
In Parkinson's, the alpha-synuclein protein misfolds and aggregates into clumps, called Lewy bodies. When Lewy bodies are found in people without Parkinson’s, it can be diagnosed as... -
Research Grant, 2020Assessing Target Engagement for Terazosin
Study Rationale:
Patients with Parkinson’s disease (PD) do not produce enough of a compound called ATP. If a person does not make enough ATP, the cells in the body can die. This is very important...
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Our funding programs support basic, translational and clinical research from academia and industry.