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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2020
    GBA Variations, Cholinergic Degeneration, and Cognitive Decline in Parkinson’s Disease

    Study Rationale:
    Mutations in the GBA gene are the most common genetic risk factors for Parkinson’s disease. People with GBA mutations (GBA-PD) may develop the disease at a younger age and may have...

  • Research Grant, 2020
    Safety and Tolerability of NLX-112 in People with Parkinson’s

    Study Rationale:
    Motor symptoms of Parkinson’s disease are caused by a lack of brain neurons that carry a neurotransmitter called dopamine, and are commonly treated with levodopa. However, after...

  • Research Grant, 2020
    Parkinson’s Disease Subtyping by Genetic and Intestinal Inflammation Biomarkers

    Study Rationale: 
    Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. Currently, no drugs are available to treat or prevent the disease because the processes...

  • Biosample Use Program, 2020
    Single-molecule Detection of Oligomeric Synuclein in Body Fluids

    Study Rationale:
    Clumps, or aggregates, of the protein alpha-synuclein have been detected in spinal fluid of people with Parkinson’s disease, where its concentration shows potential to be a biomarker...

  • Research Grant, 2020
    RT-QuIC Assay for Alpha-synuclein in Incidental Lewy Body Disease

    Study Rationale:
    In Parkinson's, the alpha-synuclein protein misfolds and aggregates into clumps, called Lewy bodies. When Lewy bodies are found in people without Parkinson’s, it can be diagnosed as...

  • Research Grant, 2020
    Assessing Target Engagement for Terazosin

    Study Rationale:    
    Patients with Parkinson’s disease (PD) do not produce enough of a compound called ATP. If a person does not make enough ATP, the cells in the body can die. This is very important...

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Our funding programs support basic, translational and clinical research from academia and industry.

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