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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant Supplement, 2020
    LIMP-2 as a Scaffolding Protein to Characterize PD-Associated GCase Variants

    Promising Outcomes of Original Grant:
    Our original grant focused on determining the structure of the complex formed by the Parkinson’s-associated protein beta-gluccocerebrosidase (GCase) and its...

  • Therapeutic Pipeline Program, 2020
    Using Vestibular Stimulation to Improve Neurovascular Status in Parkinson’s Disease

    Study Rationale:    
    Caloric vestibular stimulation activates the vestibular system, a sensory network with pathways spreading throughout the brain. The vestibular system is responsible for providing...

  • Research Grant Supplement, 2020
    Measuring LRRK2-Mediated Rab Protein in Parkinson’s Disease

    Study Rationale: 
    The discovery of LRRK2 (Leucine rich repeat kinase 2) recently as a gene that causes Parkinson’s disease has provided considerable insights into the development of both familial and...

  • Research Grant Supplement, 2020
    Discovery of Selective PET Imaging Agents for Tauopathies and Alpha-Synuclein

    Study Rationale:    
    The development of alpha-synuclein and tau imaging agents will be valuable for people with Parkinson’s disease and Frontal Temporal Dementia (FTD), as deposits of these proteins...

  • Biosample Use Program, 2020
    Mass Spectrometric Analysis of Glucocerebrosidase Protein Levels and Spinal Fluid in People with Parkinson’s

    Study Rationale:
    Mutations in the glucocerebrosidase (GBA) gene are among the most important risk factors for developing Parkinson´s disease. GBA activity is reduced in cerebrospinal fluid (CSF) of...

  • Biosample Use Program, 2020
    Adaptive Immune Markers for Predicting Cognitive Decline in Parkinson’s Disease

    Study Rationale:    
    For reasons not well understood, people with Parkinson's disease are at risk for developing dementia, a decline in memory, thinking and/or language abilities severe enough to...

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