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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2019
    Immune Cell Dysfunction in PINK1 Parkinson’s Models

    Promising Outcomes of Original Grant:
    In our previous project, we significantly advanced the characterization of PINK1 knockout (KO) models. We found evidence of innate and adaptive immune cell...

  • Research Grant, 2019
    Restoring the Nigrostriatal Pathway with Living Micto-tissue Engineered Axonal Tracts Supplement

    Promising Outcomes of Original Grant:
    The classic motor deficits of Parkinson’s disease (PD) are caused by degeneration of dopamine neurons, resulting in the loss of part of the neurons called axonal...

  • Research Grant, 2019
    Developing New 18F-based Brain Tracers for Imaging Synapse in the Human Brain

    Study Rationale:
    A synapse is a structure that allow nerve cells (neurons) to communicate with one another or with target cells. In the brain, changes in synaptic density are associated with a variety...

  • Parkinson's Global Genetics Discovery, 2019
    Genome-wide Association Study in Parkinson’s Disease Among an East Asian Population

    Study Rationale:
    The majority of the genome-wide association studies in Parkinson’s disease have included European ancestry cases and controls only, and targeted studies in East Asian populations only...

  • Research Grant, 2019
    Astrocyte Activation as a Novel Marker of Disease Progression in Parkinson’s Disease: A PET Imaging Study

    Study Rationale:
    Brain inflammation, regulated by cells called microglia and astrocytes, has been shown to play a role in the initiation and progression of Parkinson’s disease. However, the role of...

  • LRRK2 Biology Consortium, 2019
    LRRK2 Activity and Dyskinesia Supplement

    Promising Outcomes of Original Grant:
    Our preliminary funding supported exploration of the role of striatal LRRK2 in the development of levodopa-induced dyskinesia (LID). We found that inhibiting...

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Our funding programs support basic, translational and clinical research from academia and industry.

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