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MJFF Publications

The Michael J. Fox Foundation continually strives to communicate our scientific progress with the research community — through posters and presentations at meetings, in peer-reviewed scientific publications and with white paper reports.

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    The BioFIND Study (Fox Investigation For New Discovery Of Biomarkers In Parkinson's Disease): Design And Methodology (P4.043)

    Movement Disorders: Parkinson's Disease Biomarkers OBJECTIVE:To describe the study design of BioFIND, an observational, cross-sectional, multi-center study of biomarkers in moderate to advanced…
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    Combined Fenobam and Amantadine Treatment Promotes Robust Antidyskinetic Effects in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Lesioned Primate Model of Parkinson's Disease

    Movement Disorders Amantadine is currently the only drug prescribed to PD patients for counteracting levodopa-induced dyskinesia (LID) but therapeutic doses are not always efficacious and might lead…
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    Improving Patient Participation in Parkinson's Clinical Trials: The Experience of The Michael J Fox Foundation

    Clinical Investigation This article showcases MJFF's efforts to date in addressing the recruitment challenge that plagues the entire ecosystem of clinical trials in PD. By sharing MJFFs experience…
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    Loss of Leucine-Rich Repeat Kinase 2 (LRRK2) in Rats Leads to Progressive Abnormal Phenotypes in Peripheral Organs

    PLOS ONE The objective of this study was to evaluate the pathology time course of the LRRK2 knockout rat model of PD at 1-, 2-, 4-, 8-, 12-, and 16-months of age. The evaluation consisted of…
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    A Strategy for the Generation, Characterization and Distribution of Animal Models by The Michael J. Fox Foundation for Parkinson's Research

    Disease Models & Mechanisms Progress in PD research and therapeutic development is hindered by many challenges, including a need for robust preclinical animal models. Limited availability of…
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    Outcomes Summary -- Regulatory Roundtable for Cognitive Impairment in Parkinson's Disease

    Alzheimer's Research Forum This paper outlines the key takeaways and next steps from a discussion MJFF held with 24 key opinion leaders and 16 members of the FDA on mild cognitive impairment in PD …
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    Preclinical and clinical resources for Parkinson's disease research

    The Michael J. Fox Foundation for Parkinson’s Research (MJFF) is accelerating Parkinson’s disease (PD) research by decreasing barriers and increasing access to critical resources.   MJFF…
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Articles authored by Rachel Dolhun, MD, a movement disorder specialist on staff at MJFF, offer a practical review of topics related to Parkinson's disease for practicing clinicians.

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Female researcher pipetting in lab.

Breaking Research Updates

Read the latest developments in the field’s understanding and treatment of Parkinson’s disease.

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