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The Parkinson's Progression Markers Initiative is our landmark study launched in 2010 to deepen knowledge of Parkinson's and to better understand its onset and progression to speed the development of new treatments. Learn the latest news from the study here.


  • Theresa Lin, Sarah Simon, Katherine Leaver, Sonya Elango, Susan Bressman, Deborah Raymond, Rachel Saunders-Pullman

    Research Community Thanks Parkinson’s Study Participants

    Research volunteers advance understanding and treatment of Parkinson’s disease. Foundation staff and partners recently thanked local participants.
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  • Samples in the lab.

    PPMI Dispatch: Early Signs of Disease and Striking Some Potential Markers

    Findings from the Parkinson’s Progression Markers Initiative show subtle symptoms in mutation carriers and that motor subtypes change with time and therapy.
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  • Ask the PhD: Big Data, Better Answers

    In our latest Ask the PhD video, two MJFF staff scientists talk about why data matters in Parkinson’s.
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  • 'Scientific American' Talks LRRK2 and Parkinson's Research with MJFF CEO Todd Sherer

    PPMI Dispatch: Findings and New Initiatives Shared at the Annual Meeting

    Investigators from the landmark Parkinson’s Progression Markers Initiative shared recent findings and initiatives to better define, measure and treat the disease.
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  • PPMI Participant Hyam Kramer and his husband Tom posing in front of the Taj Mahal on their vacation.

    "Smart" Studies: Digital Health Tools Help Understand the Daily Parkinson's Experience

    Researchers are exploring how to utilize smartphones and smartwatches, and Parkinson's is a good test case.
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  • PPMI Shows Protein Levels Lower in Spinal Fluid of People with Parkinson's

    PPMI Dispatch: Capturing the Parkinson's Experience Day to Day and Over Years

    The Parkinson's Progression Markers Initiative is gathering and analyzing data on the experience of Parkinson's to better define and measure the disease.
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