To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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INPP5F Knockout HeLa Cell Line
HeLa cell with homozygous knockout of INPP5F.
Estimated Availability: Late 2024
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GCase Activity Probes**
GCase activity probes FQ6 and FQ10. These probes were generated and kindly shared through the MJFF Sponsored Tools Program by David Vocadlo.
Expected Availability: Mid 2024
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Human GCase Antibody (ICC)*
Monoclonal mouse anti-human GCase antibodies (clones 1/17 and 1/23) for immunocytochemistry applications.
These antibodies were generated by Roche and are kindly made available to academic/non-profit organizations only through the MJFF Sponsored Tools Program.
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Ubiquitin pS65 Phosphospecific Antibody (Ms ELISA)
Rabbit monoclonal phosphospecific antibody directed against Serine65 of mouse ubiquitin. Suitable for ELISA applications.
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Rab 10 pT73 Phosphospecific Antibody
Mouse anti-pT73 Rab10 antibody that has undergone Fc species switching to develop mouse reagents from the original rabbit antibody (MJF-R21-22-5). The new chimeric antibody is approved for immunoblotting and immunocytochemistry and can be detected using Fc-specific secondary antibodies to mouse IgG.
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Rab 10 pT73 Phosphospecific Antibody
Mouse anti-pT73 Rab10 antibody that has undergone Fc species switching to develop mouse reagents from the original rabbit antibody (MJF-R21). The new chimeric antibody is approved for immunoblotting and immunocytochemistry and can be detected using Fc-specific secondary antibodies to mouse IgG.
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BAC-Alpha Synuclein 120*
Mice conditionally express mutant human synuclein directed by the human SNCA promoter/enhancer regions on the BAC transgene that produces a C-terminal truncated protein. Model was generated and deposited by X. William Yang at University of California Los Angles through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:028808
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BAC-Alpha Synuclein*
Mice conditionally express wild-type human synuclein directed by the human SNCA promoter/enhancer regions on the BAC transgene. Model was generated and deposited by X. William Yang at University of California Los Angles through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:028806
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic