To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
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AAV1/2-CAG-Scrambled Control 3xSCRmiR/GFP
Viral Vector
CNS optimized viral vector (AAV1/2 pseudotype) encoding GFP and a scrambled control 3XmiR. To be used as a control vector with Mouse SNCA 3xmiR/GFP and Human SNCA 3xmiR/GFP. AAV 3xSCRmiR/GFP plasmid is available in the Plasmid section.
Generated as part of the Industry Tools Consortium.
Total Rab 10 Antibody
Antibody
Mouse monoclonal antibody directed against the human total Rab 10 protein. This antibody has been validated for immunoblotting experiments. This antibody epitope was mapped to amino acids 127-133.
pS65 Parkin Antibody (WB/ICC)
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine65 of Parkin. Compatible with immunoblotting and immunocytochemistry applications.
LRRK2 pS910 Phosphospecific Antibody (UDD1)
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine910 of LRRK2.
Total PINK1 Antibody
Antibody
Monoclonal antibody directed against human total PINK1. Suitable for immunoblotting experiments. The antibody was mapped to AA 188-194 with some cross-reaction to AA287-301.
Total Parkin Antibody
Antibody
Monoclonal mouse antibody directed against human Parkin. Suitable for immunoblot experiments.
LRRK2 pT1357 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine1357 of LRRK2. Antibody is suitable for immunoblotting application after immunoprecipitating for LRRK2.
LRRK2 Antibody (MJFF5)
Antibody
Rabbit monoclonal antibody directed against wild-type LRRK2. The antibody was mapped to the LRR domain of LRRK2 (AA 1035-1239).
Rab 29 Overexpression Mouse
Mouse Model
C57BL/6NTac mice constitutively over-expressing the wild type mouse Rab29 gene directed by the PGK promoter inserted via targeted mutagenesis in the ROSA26 locus.
Ubiquitinated-K266 VDAC1 Antibody
Antibody
Monoclonal antibody directed against ubiquitinated-K266 VDAC1. Please note: The antibody will not be made available as QC/QA of the antibody showed a lack of adequate sensitivity. Email tools@michaeljfox.org with questions or for more information.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic