To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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LRRK2 Antibody (N241A/34)
Antibody
Mouse monoclonal antibody directed against wild-type LRRK2 using a fragment of LRRK2 (AA 970-2527).
LRRK2 Antibody (SIG-39840)
Antibody
Mouse monoclonal antibody generated in a mouse lacking endogenous LRRK2 protein using a peptide of LRRK2 (AA 2069-2087).
LRRK2 KO Rat*
Rat Model
Homozygous rat knockout of LRRK2 created by 10 base pair deletion in Exon 30 in the Long Evans Hooded rat stain.
LRRK2 Antibody (8G10)
Antibody
Mouse monoclonal antibody directed against wild-type LRRK2 using a fragment of LRRK2 (AA 100-500)
LRRK2 D1994A Mouse
Mouse Model
Mice expressing the D1994A mutant (kinase-dead) form of LRRK2. RRID:IMSR_JAX:021830
LRRK2 Full-Length Protein (Human)
Protein
Full-Length human LRRK2 protein generated in vitro and assessed for kinase activity.
PINK1 KO Rat*
Rat Model
Homozygous rat knockout of Pink1 (PTEN-induced putative kinase 1) in the Long Evans Hooded rat strain. RRID:RGD_7241054
EIF4G1 R1207H Mouse
Mouse Model
Mice expressing the R1207H mutant form of EIF4G1. RRID:IMSR_JAX:021827
AAV1/2-CAG-Human SNCA 3xmiR/GFP
Viral Vector
CNS optimized viral vector (AAV1/2 pseudotype) encoding GFP and 3XmiR to alpha-synuclein for specific knockdown of WT human a-syn and common pathogenic mutant forms (A53T, A30P, E46K). Scrambled Control 3xSCRmiR/GFP available as a control in Reporter section and AAV Human SNCA 3xmiR/GFP plasmid available in the Plasmid section.
Generated as part of the Industry Tools Consortium.
AAV1/2-CAG-Mouse SNCA 3xmiR/GFP
Viral Vector
CNS optimized viral vector (AAV1/2 pseudotype) encoding GFP and 3XmiR to alpha-synuclein for specific knockdown of WT mouse a-syn and common pathogenic mutant forms (A53T, A30P, E46K). Scrambled Control 3xSCRmiR/GFP available as a control in Reporter section and AAV Mouse SNCA 3xmiR/GFP plasmid available in the Plasmid section.
Generated as part of the Industry Tools Consortium.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic