To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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p62 pT138 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine 138 of the p62 protein. Suitable for immunoblotting applications.
LEGEND MAX™ Human Alpha-Synuclein ELISA Kit*
Assay
ELISA kit developed in collaboration with Covance for measuring human alpha-synuclein protein in biological samples. The assay has been demonstrated to conform to AAPS performance criteria using CSF as a matrix. Please note, this assay was previously made available as an ECL ELISA but has since switched to Colorimetric.
Alpha-Synuclein 1-122 Truncation Antibody
Antibody
Rabbit monoclonal antibody directed against alpha-synuclein truncated at the 122 residue.
Estimated Availability: Early 2025
Alpha-Synuclein 1-119 Truncation Antibody
Antibody
Rabbit monoclonal antibody directed against alpha-synuclein truncated at the 119 residue.
Estimated Availability: Early 2025
Human Parkin Mouse*
Mouse Model
Transgenic mice expressing wild type human Parkin under the direction of the mouse prion protein promoter. Model was generated and deposited by Konstanze Winklhofer at Ruhr University Bochum through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:027630
Alpha-Synuclein Antibody
Antibody
Mouse anti-alpha-synuclein antibody that has undergone Fc species switching to develop mouse reagents from the original rabbit antibody (MJFR1). The new chimeric antibody is approved for immunoblotting and immunohistochemistry and can be detected using Fc-specific secondary antibodies to mouse IgG.
ATP13A2 Knockout Mouse*
Mouse Model
Mice carrying a Atp13a2 mutation resulting in disruption of exons 12 through 15 and a portion of exon 16. Model was generated and deposited by Patrick Schultheis at Northern Kentucky University through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:021914
Alpha-Synuclein Ubiquitinated at K45/48/60 Antibody
Antibody
Rabbit monoclonal antibody directed against the K45/48/60-ubiquitinated alpha-synuclein.
Estimated Availability: Late 2025
GBA E326K Knockin Mouse*
Mouse Model
Mouse expressing GBA E326K mutation and 3 silent mutations in exon 8 of the mouse Gba gene. Model was generated and deposited by Mark Cookson at NIH through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:036159
TMEM192 Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse TMEM192 for immunoprecipitation of endogenous lysosomes.
Estimated Availability: Late 2025
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic