To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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Total Parkin Antibody*
Antibody
Monoclonal mouse antibody directed against human Parkin. Suitable for immunoblot and immunohistochemistry experiments.
Total Parkin Antibody*
Antibody
Monoclonal mouse antibody directed against human Parkin. Suitable for immunohistochemistry applications, and evidence suggests this antibody may be binding to a conformational epitope.
Rab 3 pT86 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine86 of Rab3. Suitable for immunoblot applications.
LRRK2 KO MEF
Immortalized Cell
Mouse embryonic fibroblast line with knockout of LRRK2.
Expected availability: Mid 2025
LRRK2 G2019S KI MEF
Immortalized Cell
Mouse embryonic fibroblast line with knockin of the LRRK2 G2019S mutation.
Expected availability: Late 2025
LRRK2 R1441G KI MEF
Immortalized Cell
Mouse embryonic fibroblast line with knockin of the LRRK2 R1441G mutation.
Expected availability: Late 2025
LRRK2 pT1410 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine1410 of LRRK2. Antibody is suitable for immunoblotting applications.
SNCA-GFP Knockin Mouse*
Mouse Model
Mouse expressing SNCA with GFP fused to the C-terminus resulting in expression of GFP-tagged alpha-synuclein under the control of endogenous regulatory elements. Model was generated and deposited by Kelvin Luk at University of Pennsylvania through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:035412
Parkin Knockout Mouse*
Mouse Model
Homozygous knockout mice with exon 3 mutation resulting in a frame shift and a premature stop codon in exon 5. Model was generated and deposited by Jie Shen at Harvard Medical School Brigham and Women’s Hospital through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:006582
PINK1 Knockout Mouse*
Mouse Model
PINK1 knockout mice with exons 4 through 7 deleted, producing a nonsense mutation at the start of exon 8 due to a reading frame shift. Model was generated and deposited by Jie Shen at Harvard Medical School Brigham and Women’s Hospital through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:017946
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic