To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
Filters
DJ-1 KO Rat*
Rat Model
Homozygous rat knockout of DJ-1 created by 8 base pair deletion plus 1 base pair substitution in Exon 5 in the Long Evans Hooded rat strain. RRID:RGD_7241048
DJ-1 Plasmids
DNA Plasmids
DNA Plasmids encoding various DJ-1 cDNA inserts
DJ-1 proteins (recombinant proteins generated in a mammalian-optimized expression system)
Protein
The following versions of recombinant DJ-1 protein generated using a mammalian-optimized expression system are available:
- His-tagged DJ-1
- TEV-cleaved DJ-1
DJ-1 proteins (recombinant proteins generated using an E. Coli expression system)
Protein
The following versions of recombinant DJ-1 protein generated using an E. coli expression system are available:
- Untagged DJ-1
- His-tagged DJ-1
- Oxidized DJ-1
DNAJ26 Plasmids
DNA Plasmids
DNA Plasmids encoding various DNAJ26 cDNA inserts
DOX-Inducible iPSC-Derived Dopamine Neuron
Human iPS Cell
Inducible iPSC line in which addition of doxicycline to the media stimulates differentiation into dopamine neurons with 90% purity in a matter of days.
Estimated Availability: Mid 2026
Eif4g1 KO
Mouse Model
Mice carrying a targeted Eif4g1 mutation in which exons 24 through 28 are deleted. RRID:IMSR_JAX:024521
EIF4G1 R1207H Mouse
Mouse Model
Mice expressing the R1207H mutant form of EIF4G1. RRID:IMSR_JAX:021827
FLAG LRRK2 G2019S Mouse*
Mouse Model
Mice expressing FLAG-LRRK2-G2019S transgene directed by the endogenous LRRK2 promoter/enhancer regions on the BAC transgene. Model was generated and deposited by Zhenyu Yue at Mount Sinai School of Medicine through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:012467
Floxed Parkin Mouse*
Mouse Model
Mice with loxP sites flanking Parkin exon 4 for conditional knockout using Cre-expressing viral vectors. Model was generated and deposited by Dr Ted Dawson at Johns Hopkins University through the MJFF Sponsored Tools Program.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic