To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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BAC-Alpha Synuclein 120*
Mouse Model
Mice conditionally express mutant human synuclein directed by the human SNCA promoter/enhancer regions on the BAC transgene that produces a C-terminal truncated protein. Model was generated and deposited by X. William Yang at University of California Los Angles through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:028808
BAC-Alpha Synuclein*
Mouse Model
Mice conditionally express wild-type human synuclein directed by the human SNCA promoter/enhancer regions on the BAC transgene. Model was generated and deposited by X. William Yang at University of California Los Angles through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:028806
Parkin/PINK1 Double KO Rat
Rat Model
Breeding of the CRISPR Parkin KO Sprague Dawley rat with the CRISPR PINK1 KO Sprague Dawley rat to create a line with homozygous deletion of both genes.
Estimated Availability: Mid 2026
Miro1 Antibody (WB)
Antibody
Rabbit monoclonal antibody directed against human/mouse/rat Miro1, validated for use as a detector antibody in immunoblotting applications.
Mouse GCase Antibody
Antibody
Rabbit monoclonal antibody directed against mouse GCase for immunostaining applications. Antibody development failed.
Acid Ceramidase (ASAH1) Antibody
Antibody
Rabbit monoclonal antibody directed against human acid ceramidase for immunocytochemistry and immunoprecipitation applications.
FYN Protein*
Protein
Human FYN Protein. This protein was generated and shared by Drs Paul Brennan and Karolina Rygiel at Oxford University though the MJFF Sponsored Tools Program.
GAK Protein*
Protein
Human GAK Protein. This protein was generated and shared by Drs Paul Brennan and Karolina Rygiel at Oxford University though the MJFF Sponsored Tools Program.
GPNMB Protein*
Protein
Human GPNMB Protein. This protein was generated and shared by Drs Paul Brennan and Karolina Rygiel at Oxford University though the MJFF Sponsored Tools Program.
Human iPSC with HiBit-tagged VPS13C*
Human iPS Cell
Human iPSC line with HiBiT tag on the VPS13C protein and inducible LgBiT expression for live cell imaging and quantitation. Cell line was developed and kindly shared by Dr. Tom Durcan at McGill University through the MJFF Sponsored Tools Program.
Estimated Availability: Early 2o25
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic