To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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Human iPSC with HiBit-tagged GPNMB*
Human iPS Cell
Human iPSC line with HiBiT tag on the GPNMB protein and inducible LgBiT expression for live cell imaging and quantitation. Cell line was developed and kindly shared by Dr. Tom Durcan at McGill University through the MJFF Sponsored Tools Program.
Estimated Availability: Early 2025
Human iPSC with HiBit-tagged SNCA*
Human iPS Cell
Human iPSC line with HiBiT tag on the alpha-synuclein protein and inducible LgBiT expression for live cell imaging and quantitation. Cell line was developed and kindly shared by Dr. Tom Durcan at McGill University through the MJFF Sponsored Tools Program.
Human iPSC with HiBit-tagged VPS35*
Human iPS Cell
Human iPSC line with HiBiT tag on the VPS35 protein and inducible LgBiT expression for live cell imaging and quantitation. Cell line was developed and kindly shared by Dr. Tom Durcan at McGill University through the MJFF Sponsored Tools Program.
Human iPSC with HiBit-tagged LRRK2*
Human iPS Cell
Human iPSC line with HiBiT tag on the LRRK2 protein and inducible LgBiT expression for live cell imaging and quantitation. Cell line was developed and kindly shared by Dr. Tom Durcan at McGill University through the MJFF Sponsored Tools Program.
Human iPSC with HiBit-tagged Parkin*
Human iPS Cell
Human iPSC line with HiBiT tag on the Parkin protein and inducible LgBiT expression for live cell imaging and quantitation. Cell line was developed and kindly shared by Dr. Tom Durcan at McGill University through the MJFF Sponsored Tools Program.
Human iPSC with HiBit-tagged GCase
Human iPS Cell
Human iPSC line with HiBiT tag on the GCase protein and inducible LgBiT expression for live cell imaging and quantitation. Cell line was developed and kindly shared by Dr. Tom Durcan at McGill University through the MJFF Sponsored Tools Program.
INPP5F Knockout HeLa Cell Line
Immortalized Cell
HeLa cell with homozygous knockout of INPP5F.
We were unable to generate this cell line due to technical difficulty and have discontinued production.
INPP5F Protein*
Protein
Human INPP5F Protein. This protein was generated and shared by Drs Paul Brennan and Karolina Rygiel at Oxford University though the MJFF Sponsored Tools Program.
STK39 Protein*
Protein
Human STK39 Protein. This protein was generated and shared by Drs Paul Brennan and Karolina Rygiel at Oxford University though the MJFF Sponsored Tools Program.
Alpha-Synuclein N Terminal Antibody
Antibody
Rabbit monoclonal antibody directed against the N-terminal of human/mouse alpha-synuclein. Epitope has been mapped to amino acids 12-17 and 46-50 (due to sequence homology). Suitable for use in immunoblotting, immunocytochemistry, immunohistochemistry, and immunoassay.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic