To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
Filters
LRRK2 Antibody (N241A/34)
Antibody
Mouse monoclonal antibody directed against wild-type LRRK2 using a fragment of LRRK2 (AA 970-2527).
LRRK2 Antibody (8G10)
Antibody
Mouse monoclonal antibody directed against wild-type LRRK2 using a fragment of LRRK2 (AA 100-500)
LRRK2 Antibody (SIG-39840)
Antibody
Mouse monoclonal antibody generated in a mouse lacking endogenous LRRK2 protein using a peptide of LRRK2 (AA 2069-2087).
LRRK2 KO Rat*
Rat Model
Homozygous rat knockout of LRRK2 created by 10 base pair deletion in Exon 30 in the Long Evans Hooded rat stain.
LRRK2 D1994A Mouse
Mouse Model
Mice expressing the D1994A mutant (kinase-dead) form of LRRK2. RRID:IMSR_JAX:021830
LRRK2 Full-Length Protein (Human)
Protein
Full-Length human LRRK2 protein generated in vitro and assessed for kinase activity.
PINK1 KO Rat*
Rat Model
Homozygous rat knockout of Pink1 (PTEN-induced putative kinase 1) in the Long Evans Hooded rat strain. RRID:RGD_7241054
Alpha-Synuclein A30P/A53T Mouse*
Mouse Model
Transgenic mice expressing double mutant form of human alpha synuclein containing A30P and A53T under the control of the rat tyrosine hydroxylase promoter. Model was generated and deposited by Eric Richfield at Rutger’s University through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:008239
Alpha-Synuclein A53T Knockin Mouse*
Mouse Model
Double transgenic homozygous mice which have PAC overexpression of human A53T alpha synuclein mutant form on an SNCA knockout mouse background. Model was generated and deposited by Robert Nussbaum at University of California San Francisco through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:010799
Alpha-Synuclein Knockout Mouse*
Mouse Model
SCNA knockout mice carrying a 1164 bp fragment deletion in exon 2. Model was generated and deposited by Vladimir Buchman at Cardiff University School of Biosciences through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:028559
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic