To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
Filters
Alpha-Synuclein Antibody
Antibody
Rabbit monoclonal antibody directed against wild-type human alpha-synuclein. The antibody was mapped to amino acids 118-123 (VDPDNE).
LoxP LRRK2 Mouse*
Mouse Model
Mice possessing loxP sites on either side of the exon 41 of the LRRK2 gene. Model was generated and deposited by Heather Melrose at Mayo Clinic College of Medicine through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:024469
Lentiviral LRRK2 (G2019S)
Viral Vector
Lentiviral vector expressing LRRK2 mutated at residue G2019S. Lentiviral eGFP available as a control in Reporter section.
Please note: This viral vector is not intended for in vivo use.
Lentiviral LRRK2 (G2019S/D1994A)
Viral Vector
Lentiviral vector expressing LRRK2 mutated at residues G2019S and D1994A. Lentiviral eGFP available as a control in Reporter section.
Please note: This viral vector is not intended for in vivo use.
Lentiviral eGFP-LRRK2 (wild-type)
Viral Vector
Lentiviral vector encoding wild-type LRRK2 and eGFP. Lentiviral eGFP available as a control in Reporter section.
Please note: This viral vector is not intended for in vivo use.
LRRK1 KO Rat*
Rat Model
Knockout of the gene encoding LRRK1 in the Long Evans Hooded rat strain. RRID:RGD_7241057
Lentiviral eGFP
Viral Vector
Lentiviral vector encoding eGFP
Please note: This viral vector is not intended for in vivo use.
LRRK1/2 Double KO Rat*
Rat Model
Double knockout of the genes encoding LRRK1 and LRRK2 in the Long Evans Hooded rat strain. RRID:RGD_7241053
LRRK2 Antibody (UDD3)
Antibody
Rabbit monoclonal antibody directed against the N-terminus (LRRK2(100-500)) of wild-type LRRK2. This antibody has been found to be superior in immunoprecipitation of LRRK2 from a variety of cell lysates and tissues.
Parkin KO Rat*
Rat Model
Homozygous rat knockout of Parkin in the Long Evans Hooded rat strain. RRID:RGD_7241052
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic