To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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Rab 12 Antibody (IP)
Antibody
Rabbit monoclonal antibody directed against human Rab 12. Suitable for use in immunoprecipitation.
Total Rab 29 Antibody (Hu)
Antibody
Rabbit monoclonal antibody directed against the human total Rab 29 protein. Suitable for immunoblot and immunoprecipitation experiments. This antibody epitope was mapped to amino acids 141-150.
LRRK2 Wild-type Mouse
Mouse Model
Mice express a wild-type human LRRK2 gene directed by its endogenous promoter/enhancer regions on the BAC transgene. The human LRRK2 protein expression is approximately 5-fold over endogenous mouse LRRK2. RRID:IMSR_JAX:013725
LRRK2 pS955 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 955 of LRRK2.
LRRK2 G2019S Mouse
Mouse Model
Transgenic mice overexpressing a mutant form (G2019S) of human LRRK2 directed by its endogenous promoter/enhancer regions on the BAC transgene. RRID:IMSR_JAX:018785
LRRK2 R1441G Mouse
Mouse Model
Transgenic mice overexpressing a mutant form (R1441G) of human LRRK2 directed by its endogenous promoter/enhancer regions on the BAC transgene. RRID:IMSR_JAX:018786
Thy-1 Wild Type Human Alpha-Synuclein Mouse (Line 15)
Mouse Model
Transgenic mice expressing wild type human alpha-synuclein directed by the murine Thy-1 promoter. Two separate founder lines with different expression levels are available. RRID:IMSR_JAX:017682
Wild Type Human Alpha-Synuclein Mouse
Mouse Model
Mice express a wild-type human alpha-synuclein gene directed by its endogenous promoter/enhancer regions on the BAC transgene. RRID:IMSR_JAX:018442
LRRK2 KO Mouse
Mouse Model
Knockout of LRRK2 created by deletion of exons 39-40 of the LRRK2 gene in the C57BL/6N mouse strain. RRID:IMSR_JAX:016121
LRRK2 Plasmids
DNA Plasmids
DNA Plasmids encoding various LRRK2 cDNA inserts
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"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic