To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
Sponsored Tools Program
Learn more about how MJFF can help share your tools.
Tools Consortium
MJFF is working with industry to develop priority tools.
Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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TMEM175 Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse TMEM175 for immunoblotting and immunostaining applications.
Estimated Availability: Early 2025
VPS13C Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse VPS13C for immunoblotting and immunostaining applications.
Estimated Availability: Early 2025
VPS13C Knockout HeLa Cell Line
Immortalized Cell
HeLa cell with homozygous knockout of VPS13C.
Estimated Availability: Early 2025
Cathepsin B Protein
Protein
Human Cathepsin B Protein. This protein was generated and shared by Drs Paul Brennan and Karolina Rygiel at Oxford University though the MJFF Sponsored Tools Program.
Ubiquitinated-K266 VDAC1 Antibody
Antibody
Monoclonal antibody directed against ubiquitinated-K266 VDAC1. Please note: The antibody will not be made available as QC/QA of the antibody showed a lack of adequate sensitivity. Email tools@michaeljfox.org with questions or for more information.
Conditional R1441G KI Mouse*
Mouse Model
Mice designed for conditional knockin of the LRRK2 R1441G mutation. Model was generated and deposited by Dr Dario Alessi at the University of Dundee through the MJFF Sponsored Tools Program.
Estimated Availability: Late 2025
Human/Rodent Alpha-Synuclein Aggregate ELISA
Assay
ELISA kit for the measurement of human and rodent alpha-synuclein aggregates.
AAK1 pS623 Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 623 of AAK1.
Estimated Availability: Late 2025
Alpha-Synuclein Antibody
Antibody
Mouse anti-alpha-synuclein antibody that has undergone Fc species switching to develop mouse reagents from the original rabbit antibody (MJFR1). The new chimeric antibody is approved for immunoblotting and immunohistochemistry and can be detected using Fc-specific secondary antibodies to mouse IgG.
Alpha-Synuclein Ubiquitinated at K45/48/60 Antibody
Antibody
Rabbit monoclonal antibody directed against the K45/48/60-ubiquitinated alpha-synuclein.
Estimated Availability: Late 2025
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD Mayo Clinic