To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
-
Sponsored Tools Program
Learn more about how MJFF can help share your tools.
-
Tools Consortium
MJFF is working with industry to develop priority tools.
-
Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
Filters
Miro1 Antibody (ELISA-Detector)
Antibody
Rabbit monoclonal antibody directed against human/mouse/rat Miro1, validated for use as a detector antibody in immunoassay applications.
Can also be purchased as a pair with the detector antibody here.
Miro1 Antibody (ELISA-Capture)
Antibody
Rabbit monoclonal antibody directed against human/mouse/rat Miro1, validated for use as a capture antibody in immunoassay applications.
Can also be purchased as a pair with the detector antibody here.
Miro1 Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse Miro1 for immunoblotting and immunostaining applications.
Estimated Availability: Early 2025
Microtubule-Associated Protein Tau Plasmids
DNA Plasmids
DNA Plasmids encoding various MAPT cDNA inserts
MHC-I H2-Kb Antibody
Antibody
Rabbit monoclonal antibody directed against mouse MHC-I H2-Kb for immunoblotting and immunostaining applications.
Estimated Availability: Early 2025
MHC-I H2-Db Antibody
Antibody
Rabbit monoclonal antibody directed against mouse MHC-I H2-Db for immunoblotting and immunostaining applications.
Estimated Availability: Early 2025
Mfn2 LoxP Floxed Mouse*
Mouse Model
Mice with LoxP sites flanking Mfn2 exon 6. Model was generated and deposited by David Chan at California Institute of Technology through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:026525
MCU Floxed DAT-Cre Mouse*
Mouse Model
MCU Floxed DAT-Cre mice were generated by crossing floxed exons 5 and 6 of the MCU gene (Zampese et al. 2022) with mice expressing Cre recombinase under the dopaminergic-specific DAT to induce knock-out of MCU (mitochondrial Ca2+ uniporter), resulting in the loss of MCU specifically in dopaminergic cells. Model was designed by D. James Surmeier at Northwestern University and made available through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:038988
MCI-PARK Mouse*
Mouse Model
Homozygous knockout mice targeting Ndufs2 (NADH:ubquinone oxidoreductase core subunit S2) specifically in dopaminergic neurons. Mice with floxed Ndufs2 allele were crossed with mice expressing Cre recombinase under the control of Slc6ac (dopamine transporter; DAT) promoter. Model was generated and deposited by D. James Surmeier at Northwestern University through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:036313
LRRK2 Y1699C Mouse*
Mouse Model
Transgenic mice expressing LRRK2 Y1699C mutation. Model was generated and deposited by Heather Melrose at Mayo Clinic College of Medicine and Matthew Farrer at University of British Columbia through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:021913
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic