To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
-
Sponsored Tools Program
Learn more about how MJFF can help share your tools.
-
Tools Consortium
MJFF is working with industry to develop priority tools.
-
Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
Filters
LoxP LRRK2 Mouse*
Mouse Model
Mice possessing loxP sites on either side of the exon 41 of the LRRK2 gene. Model was generated and deposited by Heather Melrose at Mayo Clinic College of Medicine through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:024469
Lentiviral LRRK2 (G2019S/D1994A)
Viral Vector
Lentiviral vector expressing LRRK2 mutated at residues G2019S and D1994A. Lentiviral eGFP available as a control in Reporter section.
Please note: This viral vector is not intended for in vivo use.
Lentiviral LRRK2 (G2019S)
Viral Vector
Lentiviral vector expressing LRRK2 mutated at residue G2019S. Lentiviral eGFP available as a control in Reporter section.
Please note: This viral vector is not intended for in vivo use.
Lentiviral eGFP-LRRK2 (wild-type)
Viral Vector
Lentiviral vector encoding wild-type LRRK2 and eGFP. Lentiviral eGFP available as a control in Reporter section.
Please note: This viral vector is not intended for in vivo use.
Lentiviral eGFP
Viral Vector
Lentiviral vector encoding eGFP
Please note: This viral vector is not intended for in vivo use.
LEGEND MAX™ Human Alpha-Synuclein ELISA Kit*
Assay
ELISA kit developed in collaboration with Covance for measuring human alpha-synuclein protein in biological samples. The assay has been demonstrated to conform to AAPS performance criteria using CSF as a matrix. Please note, this assay was previously made available as an ECL ELISA but has since switched to Colorimetric.
iPLA2beta Knockout Mouse*
Mouse Model
Mice carrying a Pla2g6 mutation resulting replacement of exon 2 by a NEO cassette. Model was generated and deposited by Zemin Yao at University of Ottawa through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:023542
INPP5F pS940 Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 940 of INPP5F.
Estimated Availability: Late 2025
INPP5F Protein*
Protein
Human INPP5F Protein. This protein was generated and shared by Drs Paul Brennan and Karolina Rygiel at Oxford University though the MJFF Sponsored Tools Program.
INPP5F Knockout HeLa Cell Line
Immortalized Cell
HeLa cell with homozygous knockout of INPP5F.
We were unable to generate this cell line due to technical difficulty and have discontinued production.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic