To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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GBA D409V Knockin Mouse
Mouse Model
Knockin mice expressing the D409V mutant form of GBA on the C57BL/6N mouse background.
Generated as part of the Industry Tools Consortium. RRID:IMSR_JAX:019106
GALC Knockout A549 Cell Line
Immortalized Cell
A549 cell with homozygous knockout of GALC.
Estimated Availability: Early 2025
GALC Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse GALC for immunoblotting and immunostaining applications.
Estimated Availability: Early 2025
GAK Protein*
Protein
Human GAK Protein. This protein was generated and shared by Drs Paul Brennan and Karolina Rygiel at Oxford University though the MJFF Sponsored Tools Program.
FYN Protein*
Protein
Human FYN Protein. This protein was generated and shared by Drs Paul Brennan and Karolina Rygiel at Oxford University though the MJFF Sponsored Tools Program.
Full Length pS129 Alpha-Synuclein Protein
Protein
Phospho-S129 Alpha Synuclein semi-synthetic phosphomimetic protein generated by native chemical ligation of a recombinant peptide produced from E. coli and a synthtic peptide
Floxed S69R Rab32 Mouse
Mouse Model
Mouse expressing the S69R point mutation in the mouse Rab32 gene (corresponds to the S71R mutation in human Rab32). LoxP sites flank the Rab32 gene to enable conditional Cre-mediated knockout.
Estimated Availability: Early 2026
Floxed Parkin Mouse*
Mouse Model
Mice with loxP sites flanking Parkin exon 4 for conditional knockout using Cre-expressing viral vectors. Model was generated and deposited by Dr Ted Dawson at Johns Hopkins University through the MJFF Sponsored Tools Program.
FLAG LRRK2 G2019S Mouse*
Mouse Model
Mice expressing FLAG-LRRK2-G2019S transgene directed by the endogenous LRRK2 promoter/enhancer regions on the BAC transgene. Model was generated and deposited by Zhenyu Yue at Mount Sinai School of Medicine through the MJFF Sponsored Tools Program (available through cryorecovery). RRID:IMSR_JAX:012467
EIF4G1 R1207H Mouse
Mouse Model
Mice expressing the R1207H mutant form of EIF4G1. RRID:IMSR_JAX:021827
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic