To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
-
Sponsored Tools Program
Learn more about how MJFF can help share your tools.
-
Tools Consortium
MJFF is working with industry to develop priority tools.
-
Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
-
Alpha-Synuclein Monomer Protein for PMCA/RT-QuIC Assays
Recombinant human alpha-synuclein monomeric protein designed to serve as substrate in PMCA/RT-QuIC assays.
Estimated Availability: Late 2025
Generated as part of the Industry Tools Consortium.
-
Humanized SNCA Mouse
Mouse expressing the full human SNCA gene (including promoter, introns, and regulatory elements) without endogenous murine SNCA. Please note: MJFF was not successful in generating this line after multiple attempts. Alternative BAC human alpha-synuclein mouse lines are available at JAX.
-
Total Parkin Antibody*
Monoclonal mouse antibody directed against human Parkin. Suitable for immunohistochemistry applications, and evidence suggests this antibody may be binding to a conformational epitope.
-
Total Parkin Antibody*
Monoclonal mouse antibody directed against human Parkin. Suitable for immunoblot and immunohistochemistry experiments.
-
p62 pT138 Phosphospecific Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine 138 of the p62 protein. Suitable for immunoblotting applications.
-
RILPL1 Antibody
Rabbit monoclonal antibody directed against total rodent/human RILPL1 protein. Suitable for immunoblot, immunoprecipitation, and immunocytochemistry experiments.
-
PINK1 pS228 Phosphospecific Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 228 of PINK1.
Expected Availability: Early 2025
-
PINK1 pT257 Phosphospecific Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine 257 of human PINK1. Suitable for immunoblot applications.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic