To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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Rab 7A pS72 Phosphospecific Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 72 of the human Rab7A protein. Suitable for immunoblot and immunohistochemical experiments.
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PPMI iPSCs
Induced pluripotent stem cell (iPSC) lines are available through the PPMI repository. The repository includes lines from control, idiopathic PD, genetic PD (LRRK2, GBA, SNCA), genetic unaffected carriers (LRRK2, LRRK2/GBA, GBA, SNCA), and prodromal patients. Gene-revertant controls are available for select lines. An inventory of available lines can be found here: https://zenodo.org/records/10607589
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pT73 Rab 10 Protein
Phospho-T73 Rab10 semi-synthetic phosphomimetic protein fragment (AA66-181) generated by native chemical ligation of recombinant peptides.
Estimated Availability: Mid 2024
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Rab 10 ELISA*
ELISA kit designed for the quantitative measurement of Rab10 protein in human, mouse and rat cell and tissue extract samples.
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Rab 8A ELISA*
ELISA kit designed for the quantitative measurement of Rab8A protein in human cell and tissue extract samples.
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AAV1/2-CAG-A53T Alpha-Synuclein
Viral Vector (AAV1/2 serotype) encoding alpha-synuclein with the A53T mutation. AAV1/2 empty vector available as a control in Reporter section and the AAV-CAG-A53T alpha-synuclein plasmid is available in the Plasmid section.
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AAV1/2-CAG-empty vector
Viral Vector (AAV1/2 serotype) to serve as a control vector for the AAV1/2-CAG-A53T aSyn viral vector. The AAV-CAG-empty vector plasmid is also available in the Plasmid section.
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Ubiquitinated-K266 VDAC1 Antibody
Monoclonal antibody directed against ubiquitinated-K266 VDAC1. Please note: The antibody will not be made available as QC/QA of the antibody showed a lack of adequate sensitivity. Email tools@michaeljfox.org with questions or for more information.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic