To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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Rab 29 Overexpression Mouse
C57BL/6NTac mice constitutively over-expressing the wild type mouse Rab29 gene directed by the PGK promoter inserted via targeted mutagenesis in the ROSA26 locus.
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LRRK2 Antibody (MJFF5)
Rabbit monoclonal antibody directed against wild-type LRRK2. The antibody was mapped to the LRR domain of LRRK2 (AA 1035-1239).
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LRRK2 pT1357 Phosphospecific Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine1357 of LRRK2. Antibody is suitable for immunoblotting application after immunoprecipitating for LRRK2.
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Total Parkin Antibody
Monoclonal mouse antibody directed against human Parkin. Suitable for immunoblot experiments.
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Total PINK1 Antibody
Monoclonal antibody directed against human total PINK1. Suitable for immunoblotting experiments. The antibody was mapped to AA 188-194 with some cross-reaction to AA287-301.
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pS65 Parkin Antibody (WB/ICC)
Rabbit monoclonal phosphospecific antibody directed against Serine65 of Parkin. Compatible with immunoblotting and immunocytochemistry applications.
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AAV1/2-CAG-Scrambled Control 3xSCRmiR/GFP
CNS optimized viral vector (AAV1/2 pseudotype) encoding GFP and a scrambled control 3XmiR. To be used as a control vector with Mouse SNCA 3xmiR/GFP and Human SNCA 3xmiR/GFP. AAV 3xSCRmiR/GFP plasmid is available in the Plasmid section.
Generated as part of the Industry Tools Consortium.
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Parkin W402A KI Mouse
CRISPR/Cas9 generated mice carrying the Park2, Parkinson disease (autosomal recessive, juvenile) 2, parkin, W402A point mutation in exon 11.
Generated as part of the Industry Tools Consortium. RRID:IMSR_JAX:029317
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic