To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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HdAd5 3xFLAG-LRRK2 (wild-type)
Helper-dependent Adenovirus 5 viral vector with human synapsin promoter driving the expression of 3XFLAG-tagged WT LRRK2. HdAd5 FLAG-TK available as a control in Reporter section.
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Oxidized-DJ-1-Specific Antibody
Rabbit monoclonal phosphospecific antibody directed against oxidized DJ-1 protein.
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Cell line stably expressing wildtype LRRK2 (Type: Raw 264.7 macrophages)
Wildtype LRRK2 parental Raw 264.7 macrophage cell line to be used as a control with the mutant LRRK2 T1348N (KI) or LRRK2 (KO) macrophages.
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HdAd5 3xFLAG-LRRK2 (G2019S)
Helper-dependent Adenovirus 5 viral vector with human synapsin promoter driving the expression of 3XFLAG-tagged LRRK2 with the G2019S mutation. HdAd5 FLAG-TK available as a control in Reporter section.
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TH- GFP Rat (X-linked)
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LRRK1/2 Double KO Mouse
Double knockout of LRRK1 and LRRK2 created by deletion of exons 39-40 of the LRRK2 gene and exons 24-29 of the LRRK1 gene in the C57BL/6N mouse strain. RRID:IMSR_JAX:016122
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AAV5-CBA-eGFP
Viral vector (AAV5 serotype) encoding eGFP to serve as a control vector. Produced by the UNC Vector Core.
Characterization data for this viral vector can be found here.
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AAV5-CBA-Alpha-Synuclein
Viral vector (AAV5 serotype) encoding wild-type alpha-synuclein. Produced by the UNC Vector Core. AAV5-CBA-eGFP available as a control in Reporter section.
Limited quantities available.
Characterization data for this viral vector can be found here.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic