Dr. Gelinas received her BS in biology from The George Washington University and her PhD in biochemistry from the University of Colorado, where she studied the evolutionary basis for the telomere (a region at the end of each strand of DNA) capping complex in yeast using structural biology. Following graduate school, Dr. Gelinas accepted a position at SomaLogic, Inc. in the Technology Development group. When Dr. Gelinas joined the company, SomaLogic, Inc. was exploring the structural basis for the high affinity binding of their SOMAmer reagents (slow off-rate modified aptamers, or binding molecules) to their respective targets. Since joining SomaLogic, Dr. Gelinas has worked on several SOMAmer-protein crystallography (the study of atomic and molecular structure) projects. She continues to explore the novel structural motifs (short patterns in DNA) of SOMAmers to understand the interactions governing SOMAmer-protein interfaces. Her research helps design better binding reagents for use in research, diagnostics and therapeutics.
Associated Grants
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Identification of Slow Off-rate Modified Aptamer Reagents that Specifically Bind Phosphorylated LRRK2
2016