Dr. Joseph received his PhD degree in 1997 from the University of Lille (France). He then joined Dr. Boris Zhivotovsky´s laboratory at the Karolinska Institutet (Sweden) to investigate the cell death molecular machinery and its deficiencies in cancer cells. Thereafter, he joined the group of Dr. Thomas Perlmann at the Ludwig Institute for Cancer Research, Stockholm branch (Sweden) and studied neuronal differentiation within the context of Parkinson’s disease. He established his research group in 2004, after he received from the Swedish Research Council a junior research position. The same year, at the age of 31, he became an associate professor at the Karolinska Institutet. Over the years, Dr. Joseph was able to take advantage of this unique scientific expertise acquired during his career to develop original studies of the molecular signaling, which regulates the decision between life and death at the cellular level and how its deregulation is implicated in human diseases.