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Christian Griesinger, PhD

Chief Scientific Officer of Chemistry at MODAG GmbH

Director of the Department for NMR-based Structural Biology at Max Planck Institute for Biophysical Chemistry

Location: Gottingen Germany

Christian Griesinger, Dr. phil., is author of more than 310 publications. He studied chemistry and physics and received a PhD in chemistry in 1986. After a postdoctoral fellowship at the physical chemistry laboratory of ETH Zürich with later nobel laureate Richard Ernst, he was appointed (1990) as full professor of organic chemistry at University of Frankfurt and as director at the Max Planck Institute for Biophysical Chemistry (1999). He develops methods in nuclear magnetic resonance and applies them to structure investigations of small molecules and proteins, specifically intrinsically disordered proteins such as alpha-synuclein, a key player in Parkinson’s disease. Modifying alpha-synuclein’s structures by small molecules lead to the joint research program with Dr. Armin Giese and the discovery and patenting of anle138b and the co-founding MODAG GmbH in 2013. He was awarded the Sommerfeld (1997), Leibniz (1998), Bayer (2003), Elhuyar-Goldschmidt (2011), Bücher (2012) and Ampere (2014) prizes and an ERC advanced grant (2008). 


Associated Grants

  • Study of Drug Binding Sites in Alpha-synuclein Fibrils

    2016


  • Evaluation of the Oligomer Modulator anle138b in a Seeding-based Model of Parkinson’s Disease

    2014


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