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Darren J. Moore, PhD

Professor, Center for Neurodegenerative Science at Van Andel Research Institute

Location: Grand Rapids, MI United States

Darren Moore leads the Laboratory of Molecular Neurodegeneration at the Van Andel Institute. His research focuses on investigating the pathophysiological mechanisms of gene products associated with inherited forms of Parkinson’s disease, in particular, the LRRK2 and VPS35 genes. Dr. Moore received his PhD in molecular neuroscience from the University of Cambridge in 2001 and conducted postdoctoral research at the Johns Hopkins University School of Medicine. He joined the faculty of the Department of Neurology at Johns Hopkins in 2006 as an assistant professor. Dr. Moore moved to the Brain Mind Institute of the Swiss Federal Institute of Technology (EPFL) in 2008 as an assistant professor of Life Sciences. In 2014, he became an associate professor in the Center for Neurodegenerative Science at the Van Andel Institute in Michigan. He was promoted to rull professor in 2017 and currently serves as the inaugural chair of the Department of Neurodegenerative Science.


Associated Grants

  • Evaluation of ATP13A2 as a Molecular Target for Ameliorating Alpha-Synuclein-Induced Neurodegeneration in Pre-clinical Models of PD

    2011


  • Validation of Enzymatic Activity and Neuropathology in G2019S LRRK2-induced Dopaminergic Neurodegeneration in a Pre-clinical Model of Parkinson's Disease

    2010


  • Identification of LRRK2 Substrates in Pre-clinical Models of Parkinson's Disease

    2009


  • Generation of Transgenic Mice with Selective and Progressive Loss of Nigrostriatal Dopaminergic Neurons

    2006


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