Dr. Masliah received his MD in 1982, completed his residency in pathology at the National Institutes of Health in Mexico City in 1986 and a fellowship in neuropathology at the UC, San Diego in 1989. Dr. Masliah is currently professor at the Departments of Neurosciences and Pathology at UC, San Diego and director of the Autopsy Service at the UCSD-Medical Center. Dr. Masliah has published over 500 research articles. His laboratory investigates the molecular mechanisms of synaptic degeneration in Parkinson’s and Alzheimer’s diseases and is actively involved in developing novel treatments for these devastating disorders. Dr. Masliah’s laboratory was one of the first to develop a transgenic pre-clinical model for Parkinson’s and Alzheimer’s diseases and at identifying alpha-synuclein as a major contributor to the pathogenesis of these disorders. The Masliah laboratory is currently developing new treatment for Parkinson’s disease using small molecules that block accumulation of toxic alpha-synuclein in the brain.
Associated Grants
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A Pre-Clinical Study in a PD-like Transgenic Pre-Clinical Model of a Novel Isoindole Compound that Selectively Blocks Alpha-Synuclein Oligomerization
2010
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